CAS103-33-3
EINECS203-102-5化學(xué)式C12H10N2
分子量182.22InChIInChI=1/C12H10N2/c1-3-7-11(8-4-1)13-14-12-9-5-2-6-10-12/h1-10H密度1.09 g/mL at 25 °C (lit.)熔點(diǎn)65-68 °C (lit.)沸點(diǎn)293 °C (lit.)閃點(diǎn)100 °C水溶性Soluble in alcohol, ether, benzene and glacial acetic acid.Insoluble in water.蒸汽壓1 mm Hg ( 104 °C)溶解度6.4毫克/升折射率1.62662 (78.1℃)存儲(chǔ)條件room temp穩(wěn)定性穩(wěn)定。可燃。與強(qiáng)氧化劑不相容。對(duì)空氣和光敏感。敏感性Sensitive to humidity外觀結(jié)晶性粉末顏色OrangeMerck14,917BRN1819138物化性質(zhì)橙紅色片狀結(jié)晶體。熔點(diǎn)為68.5℃，沸點(diǎn)為293℃，相對(duì)密度為1.203(20/4℃)，折光率1.6266。能溶于醇、醚、苯和冰醋酸，不溶于水。MDL號(hào)MFCD00003022體外研究Photochromic compounds that undergo large conformational changeswhen exposed to light of appropriate wavelength are particularlyattractive as molecular switch elements. Azobenzene is a popularchoice among the chromophores. The thermodynamically favored transisomer is rapidly converted to the cis isomer by irradiation at thewavelength of the π-π* transition, whereas the reverse process isachieved either (slowly) by thermal relaxation in the dark or() by irradiation at the wavelength of the n-π* transition.The azobenzene amino acid (aa) can be used as a photo-inducibleconformational switch in polypeptides. A reversible conformationalchange of the peptide backbone is induced by switching between thecis and trans configurations of the azobenzene moiety byirradiation with light of suitable wavelength. Azobenzene has beenthe most widely used optical trigger for the synthesis ofphotoresponsive systems ranging from poly-a-amino acids toinnovative materials with light-controlled mechanical and opticalproperties. Its use in form of appropriate derivatives allow togenerate cyclic peptide structures of constraint conformationalspace and thus to exploit its reversible photoisomerization toinduce well defined transitions between different conformationalstates. Azobenzene photoswitches can be used to drive functionalchanges in peptides, proteins, nucleic acids, lipids, andcarbohydrates.危險(xiǎn)品標(biāo)志T - 有毒物品
N - 危害環(huán)境的物品
Xn - 有害物品
F - 易燃物品
風(fēng)險(xiǎn)術(shù)語(yǔ)R45 - 可能致癌。
R20/22 - 吸入及吞食有害。
R48/22 - 吞食長(zhǎng)期接觸嚴(yán)重危害健康。
R50/53 - 對(duì)水生生物有極高毒性，可能對(duì)水體環(huán)境產(chǎn)生長(zhǎng)期不良影響。
R68 - 可能有不可逆后果的危險(xiǎn)。
R67 - 蒸汽可能引起困倦和眩暈。
R65 - 吞食可能造成肺部損傷。
R62 - 有損害生育能力的危險(xiǎn)。
R51/53 - 對(duì)水生生物有毒，可能對(duì)水體環(huán)境產(chǎn)生長(zhǎng)期不良影響。
R38 - 刺激皮膚。
R11 - 高度易燃。
R48/20 -
R39/23/24/25 -
R23/24/25 - 吸入、皮膚接觸及吞食有毒。
R52/53 -
安全術(shù)語(yǔ)S53 - 避免接觸，使用前須獲得特別指示說(shuō)明。
S45 - 若發(fā)生事故或感不適，立即就醫(yī)(可能的話，出示其標(biāo)簽)。
S60 - 該物質(zhì)及其容器須作為危險(xiǎn)性廢料處置。
S61 - 避免釋放至環(huán)境中。參考特別說(shuō)明/安全數(shù)據(jù)說(shuō)明書(shū)。
S62 - 若吞食，切勿催吐；立即求醫(yī)，并出示其容器或標(biāo)簽。
S36/37 - 穿戴適當(dāng)?shù)姆雷o(hù)服和手套。
S33 - 采取措施，預(yù)防靜電發(fā)生。
S29 - 切勿倒入下水道。
S16 - 遠(yuǎn)離火源。
S9 - 保持容器置于良好通風(fēng)處。
S7 - 保持容器密封。
危險(xiǎn)品運(yùn)輸編號(hào)UN 3077 9/PG 3WGK Germany3RTECSCN1400000TSCAYes海關(guān)編號(hào)29270000Hazard Class6.1(b)Packing GroupIII