萬(wàn)古霉素 化學(xué)試劑 貫穿式服務(wù) 全國(guó)送貨 行業(yè)顛覆者 品質(zhì)實(shí)力 1404-90-6-一個(gè)添下面兩個(gè)吃奶把腿抬高-韓國(guó)電影失足美女色誘獵物
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- 1404-90-6
| 密度 | 1.2882 (rough estimate) |
| 熔點(diǎn) | >274°C (dec.) |
| 溶解度 | DMSO (微溶) |
| 折射率 | 1.7350 (estimate) |
| 酸度系數(shù) | pKa 2.18±0.08(H2Ot = 25.0±0.1I = 0.2 (NaCl)N2 atmosphere)(Uncertain);7.75±0.02(H2Ot = 25.0±0.1I = 0 |
| 存儲(chǔ)條件 | 2-8°C |
| 穩(wěn)定性 | 吸濕性 |
| 外觀 | 固體 |
| 顏色 | Off-White |
| 體外研究 | Vancomycin is a large glycopeptide compound with a molecular weightof 1450 Da. Vancomycin is a unique glycopeptide structurallyunrelated to any currently available antibiotic. It also has aunique mode of action inhibiting the second stage of cell wallsynthesis of susceptible bacteria. Vancomycin is active against alarge number of species of Gram-positive bacteria, such asStaphylococcus aureus, Staph. epidermidis, Str. agalactiae, Str.bovis, Str. mutans, viridans streptococci, enterococci . |
| 體內(nèi)研究 | Vancomycin is administered intravenously, with a standard infusiontime of at least 1 h, to minimize infusion-related adverse effects.Subjects with normal creatinine clearance, vancomycin has anα-distribution phase of 30 min to 1 h and a β-elimination half-lifeof 6-12 h. The volume of distribution is 0.4–1 L/kg. The binding ofvancomycin to protein ranges from 10% to 50%. Factors that affectthe overall activity of vancomycin include its tissue distribution,inoculum size, and protein-binding effects. Vancomycin treatment ofinfected mice is associated with improved clinical, diarrhea, andhistopathology scores and survival during treatment. |
1404-90-6 , 萬(wàn)古霉素 , C66H75Cl2N9O24 , 萬(wàn)古霉素堿 , 萬(wàn)古霉素AR
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